Two postdoctoral fellow/researcher positions applying gene editing in production species

The Norwegian University of Life Sciences (NMBU)

NMBU has a special responsibility for research and education that ensures the basis of life for future generations.

Sustainability is rooted in everything we do and we provide knowledge for life.

NMBU has 1700 employees and 5200 students and is organized in seven faculties. NMBU has a campus in Ås and in Oslo. In the autumn of 2020 we are co-located on Ås.

Further information on NMBU is available at www.nmbu.no

About the position

The Department of Animal- and Aquacultural Sciences ( IHA ), Faculty of Biosciences ( BIOVIT ), at the Norwegian University of Life Sciences (NMBU) is inviting applications for two 3-year postdoctoral fellow / researcher positions implementing gene editing techniques (eg. CRISPR-Cas9) to address specific biological questions relevant to then Norwegian breeding industry.

The successful candidate will work within the research project “Gene Editing to Innovate Norwegian Breeding Industries ( GENEinnovate )”, recently funded by the BIONÆR program in the Research Council of Norway.

The successful candidate will join CIGENE , a multidisciplinary genome biology research group possessing expertise in genetics, evolutionary and comparative genomics, bioinformatics and systems biology. Located within the Department of Animal- and Aquacultural Sciences, this group includes 2 full-time professors, 2 associate professors, 1 center coordinator, 11 researchers, 4 postdocs, 8 PhD students and 10 research technicians.

CIGENE has a strong aqua- and agri- research profile, with key strengths in the application of ‘omics’ data to understand the genetic architecture of complex traits. The group wishes to use functional genomics technologies, including gene editing, in order to better understand the biology underlying specific genotype-phenotype associations. CIGENE has excellent wet and dry lab facilities for automated high-throughput omics, and bioinformatics.

Main tasks

The GENEinnovate project seeks to lay the technical foundations for applied gene-editing by exploring industry challenges in a laboratory setting. Initially we will use GE as a tool to test specific hypothesized genotype-phenotype associations in biological material (cells/embryos) from commercial fish, pig, cattle and plant populations.

The successful applicants will work in a newly established team (including plant and animal researchers, postdoctoral fellows and students) and will be expected to spearhead the integration of GE protocols including, but not limited to:

(i) constructING design and production

(ii) developing and maintaining relevant cell lines

(iii) optimizing transfection,

(iv) validating construct delivery and function, etc..

During the period of employment, we anticipate a growing need to develop high-throughput approaches for developing constructs, screening transformants and functional testing and anticipate that the candidates will lead this activity.

Qualifications and skills

Required academic qualifications:

  • PhD-degree in functional genomics, molecular biology, cell biology, or similar
  • Recent practical lab experience focusing on cell culture and cell biology techniques, and molecular biology
  • Excellent communication skills both to the scientific community and to a broader audience

Desired academic qualifications:

  • Broad, practical experience with CRISPR-Cas9 or other gene editing approaches
  • Immunology knowledge
  • Proven ability to develop/optimize/adapt lab protocols, and to record and disseminate these to others
  • Experience isolating cells and establishing primary cell lines
  • Experience with analyses of genomics/transcriptomics/epigenomics data
  • Knowledge of microscopy, western blotting, plasmid vector construction

Required personal skills:

  • Understanding for the goal of the work and ablity to orient the time and energy on the most critical questions without compromising the attention to details
  • Ability to work co-operatively with others; desire to be a part of a team and contribute to organizational and team goals, effective communication with team members
  • Enthusiastic, highly structured and organized, able to multi-task
  • Ability for independent work displaying initiative and careful creative thought
  • Analytical and academic approach to research questions
  • Good collaborative and social skills
  • Applicants must be proficient in English, both written and spoken. Proficiency in Norwegian is not required but is advantageous.

Remuneration and information

The position is placed in government pay scale position code 1352 Postdoctoral Fellow, wage framework 24, salary grade 59-77 (NOK 515 200 - 731 400), depending on qualifications. Seniority Promotion in position.

For further information, please contact project leader Dr. Matthew Kent by email: matthew.peter.kent@nmbu.no , or phone +47 4736-2026, or group leader prof. Sigbjørn Lien by email: sigbjorn.lien@nmbu.no , or phone +47 9135-3715.

Information to applicants

Application

To apply online for this vacancy, please click on the 'Apply for this job' button above. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Applications should include (electronically) a letter of intent, curriculum vitae, full publication list, copies of degree certificates and transcripts of academic records (all certified), and a list of two persons who may act as references (with phone numbers and e-mail addresses).

Application deadline: May 5th 2019

Up to ten publications selected by the applicant as most relevant must be attached to the application. If it is difficult to identify the contribution of the applicant in multiple-author publications, a short explanation about the applicant’s part of the work is suggested.

Applicants invited for an interview will be asked to present verified copies of diplomas and certificates.

About BIOVIT

BIOVIT is organized into two departments: Department of Animal and Aquacultural Sciences and Department of Plant Sciences .

The main objective of BIOVIT is to contribute to the development of sustainable agriculture and food production systems through basic and applied research on plants and animals including fish (aquaculture). The faculty houses Centre for Integrative Genetics (CIGENE) and the research center for Research-based Innovation (SFI) – Foods of Norway.

The faculty is responsible for bachelor- and master programmes in Biology, Animal Science and Plant Science, and international master programmes in Agroecology, Plant Science, Aquaculture, Animal Breeding Genetics and Feed Manufacturing Technology. PhD programmes include Animal Science and Aquaculture, and Plant Sciences. There are currently 480 bachelor and master students, and 90 PhD students, enrolled in these programmes. The faculty has approximately 220 permanent and temporary scientific employees, including technicians, and 18 administrative positions.


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Norwegian University of Life Sciences (NMBU)

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